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Oxymatrine 41 cases of chronic hepatitis B
4 Editor: Wei Yi) external application of Chinese medicine combined with western treatment Yongquan inflammation syndrome in 40 cases of infant JLEF Huiluo Lan Tang 1 Yuan Hao Guozhen Chinese medicine hospital in Hubei Province (Wuhan, 430061, China) 2, Wuhan General Hospital of the military in May 1995 to 2001 5 month we were treated 80 cases of infantile hepatitis syndrome income children in two different ways of treatment,[link widoczny dla zalogowanych], and were compared, of which the external application of Chinese medicine treatment group significantly, which will now report the following observations. 1 General Information 1.1 clinical data of 80 cases 67 cases of male children and 13 females, diagnostic criteria are in line with the 5th in 1995 National Conference on infectious parasitic diseases revised standards. Age 1 - 2 months in 43 cases, 2 to 3 months in 31 cases, 3 to 4 months in 6 cases. 80 patients were randomly divided into two groups 40 patients, two groups of infants in gender, age, illness, no significant difference in duration, is comparable. The youngest were 30 days. The largest in 4 months. 1.2 All patients had clinical manifestations of jaundice, in which 17 patients with mild and moderate jaundice. 63 cases of severe jaundice. Onset reduced more than a nurse, nausea, galactorrhea, pale yellow or gray color stool; liver palpation are more than the normal range,[link widoczny dla zalogowanych], accompanied by splenomegaly in 20 cases. Different degrees of liver function abnormalities: A78 ~ 680U / L,[link widoczny dla zalogowanych], AST60 ~ 150U / L,[link widoczny dla zalogowanych], ALP180 ~ 310U / L; total bilirubin 100 ~ 220pmol / L, direct bilirubin 49 - 98pmol / L. Cytomegalovirus infection in 17 cases positive for IgM, IgG positive in 9 cases; PCR, HBVDNA positive, Ht3s ~, HBeAg, HBcAg, anti-HBC were a positive 21; blood culture positive diagnosis of sepsis in 3 cases; intracranial hemorrhage in 5 cases, the respiratory tract infection in 11 cases, 6 cases of diarrhea, anemia in 25 cases. B-test liver and spleen, showed liver echo uniform, part of the echo is slightly enhanced. 2 treated 40 patients with treatment using self-made Chinese medicines (capillaris, Gardenia, skullcap and other drug composition of the 1) of about 5g, plus Vaseline cream applicator adjustment springs, 1 / d, the cover gauze, adhesive plasters to fixed, clockwise rubbing 30 times, sooner or later, the 1st, 14 days for a course of treatment. At the same time combined with Western medicine antibiotics, adrenal cortex hormones and energy mixture intravenous drip of positive CMV IgM plus ganciclovir. Control group, 40 cases were treated with antibiotic medicine, adrenal cortex hormones and energy mixture intravenously, 1 / d, oral luminal another 14 days for a course of treatment. 3 standard clinical cure efficacy: symptoms, jaundice, liver function returned to normal. Liver and spleen size in the normal range. Improved: jaundice reduced part of the normal or improved liver function, liver and spleen size close to the normal range. Invalid: Symptoms, signs and liver function was not improved. 4 treated 21 patients the treatment group were cured (52.5%); improved in 16 patients (40%); 3 cases (7.5%); the total effective rate was 92.5%,[link widoczny dla zalogowanych], the average healing time was 11.2 days . Control group, 17 patients were cured (42.5%); improved in 13 cases (32.5%); 3 cases (7.5%); the total rate was 75%, the average healing time was 13 days, after statistical processing, the two groups and the total effective cure rate differences were significant (all P <0.05). 5 Discussion National / bJl ~ Viral Hepatitis Prevention Conference was in 1982, all infants less than 1 year of age (including newborns) caused due to various causes of jaundice, liver dysfunction and hepatosplenomegaly as the main manifestation II Fou bed infant hepatitis syndrome syndrome is named, the pathogen mostly hepatitis B virus (HBV) and cytomegalovirus (CMV), a small number of EB virus (EBV), herpes simplex virus (HSV), rubella virus, enterovirus, etc. can also be caused by bacterial infection. Chinese medicine, infantile hepatitis syndrome Jaundice is caused by biliary Taidu deter heat, Chinese medicine, Artemisia capillaris, Gardenia, skullcap with heat, detoxification, dampness, the role of jaundice, animal experiments show that the mechanism is the induction of hepatic enzymes increased hepatic of bilirubin uptake, binding and excretion, reduce liver inflammation and prevent liver cell degeneration, necrosis, and promote repair and regeneration of liver cells, and enhance liver detoxification, and promote liver metabolism; but also has a strong anti-viral capacity, can inhibit the activity of many viruses. 3 Yongquan topical herbal medicine, medicine is absorbed through the hole to stimulate qi, dredge the meridians, promoting qi, yin and yang, regulating body functions and organs, and play a conditioning blood, to cure the disease features. External application of Chinese medicine may be given medicines to eliminate the difficulties, infusion reactions, no side effects, patients easily accepted, a significant effect and should be introduced.
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